Greater activation of crucial oncogenic signalling pathways (PI3K/AKT, RAS/MAPK and MYC) upstream of ribosome biogenesis constitutes yet another hallmark of HGSC,9 and we hypothesise that inhibiting ribosome biogenesis can provide a powerful cancer therapeutic selection.10 In fact, we have demonstrated encouraging responses with the ribosomal RNA gene (rDNA) transcription inhibitor https://cdk2-in-444220.therainblog.com/30906986/5-simple-techniques-for-remodelin