Pentobarbital will lower the level or effect of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Small/Significance Not known. pentobarbital decreases levels of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can decrease panobinostat degrees by ~70% and bring about therapy failure. pentobarbital will reduce... https://remingtonncnxh.verybigblog.com/30457896/what-does-is-nembutal-a-depressant-mean