Biologics. Biologics are genetically engineered proteins that focus on unique elements of the immune method that gasoline inflammation. Additional treatment method possibilities like bDMARDs, tsDMARDs, biosimilars or mixture therapy can be obtained when csDMARDs are ineffective or inadequately tolerated. bDMARDs are a more recent option for the treatment of RA https://www.directivepublications.org/journal-of-arthritis-and-rheumatology/